Virgin Radio is using Drupal for a number of websites. Example: http://www.virginradio999.com.
I'm excited by this because I'm a Richard Branson fan. There, I have said it. He is one of the greatest entrepreneurs of our time. He proves that you can do well, do good, and have a great time doing it — which is exactly how I like to run Drupal, Acquia and Mollom. I you haven't read his book yet, you should!